Download pdf nanofluidics and microfluidics free online. Systems and applications article pdf available in ieee sensors journal 85. The threshold field strength required to drive transport, the threading. The laboratory of physical chemistry of modified surfaces was created by the a. Nov 29, 2014 an electrokinetically driven deterministic lateral displacement device is proposed for the continuous, twodimensional fractionation of suspensions in microfluidic platforms. Universityofljubljana facultyofmathematicsandphysics departmentofphysics seminar microfluidics author. Electrokinetically driven microfluidics and nanofluidics 1st edition by hsuehchia chang author, leslie y.
Although the first electrokinetic phenomenon is observed more than twocentury. Fluid is a substance that continually flows under an applied shear stress fluidics. Electrokinetically driven concentration of particles and cells by dielectrophoresis with dcoffset ac electric field. Microfluidics has recently emerged as a new technology for studies at the small scale ranging from the biological sciences, soft matter, reactions and synthesis, highthroughput drug screening, encapsulation, and labonchip diagnostics whitesides, 2006. Most microfluidic and nanofluidic devices with liq uid flows are driven by electric fields and fall under the category of electrokinetic flows. Electrokineticallydriven microfluidics and nanofluidics by hsuehchia chang, 9780521860253, available at book depository with free delivery worldwide. Surface tensiondriven flow surface tensionpowered self. Fluid motion in these chemical biochip systems is often achieved using electroosmotic flow. Electrokinetically driven deterministic lateral displacement. The field of nanofluidics is widely known as the research and application of the behaviors of liquid flow in a specific area that is confined to the nanoscale 1.
However, the flow rate supplied by the nanofluidic channel is sometimes not adequate. Towards practical translation of acousticallydriven microfluidic devices. Nanofluidics have had a significant impact in biotechnology, medicine and clinical diagnostics with the development of labonachip devices for pcr and related techniques. An equation of motion under combined pressure and electricallydriven flow can then be.
Electrokinetically driven microfluidics and nanofluidics electrokinetics is currently the mechanism of choice for. Electrokinetically driven microfluidics and nanofluidics cambridge univ press, 2009. Concepts for resolving git conflicts refer to vimdiff if you still use the keyboard commands for gvim. The surface charge and potentials are depicted based on the theories developed over the past century figure from 1 surfacemodified microfluidics and nanofluidics 26 s s. Microfluidics and nanofluidics, volume 5, issue 6 springer. Objectives the primary objectives of the course are as follows. Electrohydrodynamic atomization, electrospinning and discharge driven vortices. Smallest fluid quantities single cell high throughput statistics faster physicochemical processes diffusion more efficient towards quantitative biology.
Nanoscale electrokinetics and microvortices university of notre. Electrokinetic flow in a narrow cylindrical capillary. Chang, h and yeo, l 2010, electrokinetically driven microfluidics and nanofluidics, cambridge university press, new york, united states. November 19, 2010 jongho lee wins the best poster award out of 162 posters at the 2010 asme congress. Dec 12, 2012 the electrophoretically driven transport of doublestranded. The objectives of the journal are to 1 provide an overview of the current state of the research and development in microfluidics, nanofluidics and labonachip devices, 2 improve the fundamental understanding of microfluidic and nanofluidic phenomena, and 3 discuss applications of microfluidics, nanofluidics and labonachip devices. An electrokinetically driven deterministic lateral displacement device is proposed for the continuous, twodimensional fractionation of suspensions in microfluidic platforms.
Leslie yeo is the author of a thousand and one first nights 0. Leslie yeo author of electrokinetically driven microfluidics. The talks were centered around three main topics, namely, fundamentals in microfluidics, fundamentals in nanofluidics, and their applications particularly in biological engineering. In this work, we simulate electrokinetically driven transport of unretained solute bands in a variety of twodimensional spatially periodic geometries post arrays as well as sinuousvaricose channels, in the thin debye layer limit. Nanofluidics is the study of the behavior, manipulation, and control of fluids that are confined to structures of nanometer typically 1100 nm characteristic dimensions 1 nm 10. Nanochannels were fabricated having critical dimensions width and depth corresponding to 0. Microfluidics and nanofluidics, volume 12, issue 5 springer. Pdf the applications of electrokinetics in the development of microfluidic devices have been widely. Pressure driven ow is commonly found in uid systems. Amazon advertising find, attract, and engage customers. The electrophoretically driven transport of doublestranded.
Electrokineticallydriven microfluidics and nanofluidics edition 1 available in hardcover. Electrokineticallydriven microfluidics and nanofluidics edition 1. Flow control in microfluidic devices i nanofluidics, microfluidics and millifluidics nanofluidics is the study of the behavior, manipulation, and control of fluids that are confined to structures of nanometer typically 1. Conference on advances in microfluidics and nanofluidics.
Optoelectrical microfluidics as a promising tool in biology. The new laboratory was composed from the parts of laboratories of surface forces formerly directed by professor boris v. Electrokineticallydriven transport of dna through focused. Electrokinetics in microfluidics, volume 2 1st edition. Electrokinetically driven microfluidics and nanofluidics electrokinetics is currently the mechanism of choice for fluid actuation and bioparticle manipulation at microscale and nanoscale dimensions. Nanofluidic devices have unique capabilities for manipulation and sensing of dna molecules at the singlemolecule level. Exosomes are a specific subpopulation of extracellular vesicles that have gained interest because of their many potential biomedical applications. The objectives of the journal are to 1 provide an overview of the current state of the research and development in microfluidics, nanofluidics and labona. Nielsen book data summary electrokinetics is currently the mechanism of choice for fluid actuation and bioparticle manipulation at microscale and nanoscale dimensions. Electrokinetically driven microfluidics and nanofluidics rmit research repository this text aims to provide a comprehensive treatise on both classical equilibrium electrokinetic phenomena as well as the more recent nonequilibrium phenomena associated with both dc and ac electrokinetics in the context of their application to the design of. Pressure driven flow in microfluidics devices often requires components with. With attention to the fundamentals as well as advanced applications of fluidics, this book imparts a solid knowledge base and develops skills for future problemsolving and.
Christoffel transform, and transport is modeled using a monte carlo method in. Microfluidics and nanofluidics linkedin slideshare. An electrokinetically driven deterministic lateral displacement edld device is proposed for the continuous, twodimensional fractionation of suspensions in microfluidic platforms. The invited speakers are leading microfluidics and nanofluidics researchers in physics, chemistry and the various engineering disciplines. It is the hope of the organization committee that this will be the first of a regular pacific rim conference on the topics. Nov 30, 2009 electrokinetically driven microfluidics and nanofluidics by hsuehchia chang, 9780521860253, available at book depository with free delivery worldwide. Attempts have been made to understand the behaviour of flowfields around nanoparticles in terms of fluid forces as a function of reynolds and knudsen number using. Electrokinetically driven microfluidics and nanofluidics. Electrokinetic pumps utilize a static electric field for pumping conductive fluid. Microfluidics is ushering a new era in drug discovery 1, biological analysis, and pointofcare diagnostics 2,3. It is essential reading for upperlevel undergraduates and graduate students in engineering and professionals in industry. Spring me 599c structure and rheology of complex fluids, 3 credits professor amy shen complex fluids are a broad class of materials that have a microstructure that is much. Electric field driven pumping in microfluidic device ncbi.
There has recently been widespread interest in the use of ac electric fields, given the many advantages it offers over dc electrokinetics. Electrokinetics is currently the mechanism of choice for fluid actuation and bioparticle manipulation at microscale and nanoscale dimensions. Buy electrokineticallydriven microfluidics and nanofluidics on. Small volumes small size low energy consumption use of special phenomena. Gale fundamentals of micromachining microfluidic system concept concept one system to provide all of the possible required analyses for a given type problem all processing steps are performed on the chip no user interaction required except for initialization portable bedside systems possible labonachip. This barcode number lets you verify that youre getting exactly the right version or edition of a book. Grant of the institute for the promotion of innovation through science and technology in flanders iwtvlaanderen, by the fund for scientific research flanders fwo g. Microfluidics and nanofluidics presented by saakre manjesh manglam arya 2. Dongqing li is the professor of microfluidics and nanofluidics at the waterloo institute for nanotechnology at the university of waterloo.
Journal of microfluidics and nanofluidics journal metrics 2015 days from submission to first decision number of days from submission of a manuscript to first decision. Design optimization of an enzymatic assay in an electrokinetically driven microfluidic device y. Interface tracking interfacial electrohydrodynamics. Pdf electrokinetic mixing in microfluidic systems researchgate. Theory and selected applications offers an accessible, broadbased coverage of the basics through advanced applications of microfluidics and nanofluidics. Frumkin ipce ras in 1989 after the department of surface phenomena was closed with the retirement of professor boris v. As the name suggests, microfluidics involves fluid flows at. Volume 19 issue 3 fluidics was also held, chaired by professor robert austin princeton university.
Electrokinetic flow diagnostics stanford university. Electrokinetically driven microfluidics and nanofluidics in. Younga electroosmotic flow analysis of a branched uturn nanofluidic. Sounds like youre doing a threeway merge, so a should be the base revision that b and c are based on, b is theirs and c is yours i believe. An electrokineticallydriven deterministic lateral displacement edld device is proposed for the continuous, twodimensional fractionation of suspensions in microfluidic platforms. Electrokineticallydriven deterministic lateral displacement. Fluids confined in these structures exhibit physical behaviors not observed in larger structures, such as those of micrometer dimensions and above, because the characteristic physical scaling lengths of. Providing the basic knowledge on the underlying physics of electrokinetically driven flow at microscale level. Overview free surfaces are commonly encountered in many micro. Fundamentals, theories and applications overview the ion and fluid transport phenomena through microfluidic systems draws a great attention to the world wide researches due to its versatile applications ranging from the industries of. Nanofluidics is the study of the behavior, manipulation, and control of fluids that are confined to.
By performing desired analysis in picoliter to nanoliter volumes at high throughput, microfluidic devices outperform some of the conventional benchtop technologies. May 09, 2019 electrokinetically driven microfluidics and nanofluidics pdf for conflicts it shows a questionmark. Mar 01, 2010 9780521860253 electrokinetically driven microfluidics and nanofluidics. In our example the history entry start contains first the version info with reg. There has recently been widespread interest in the use of ac electric. Electrokinetically driven flow reversepolarity substrate material. An important class of microfluidic systems is systems that aim to perform basic chemical assays and other processing steps on a fluidic chip. Electric field driven pumping in microfluidic device.
Dispersion of solute by electrokinetic flow through post. Universityofljubljana facultyofmathematicsandphysics departmentofphysics. The suspended species are driven through an array of regularly spaced cylindrical posts by applying an electric field across the device. Transport phenomena in nanofluidics infoscience epfl. Microfluidics concerns the manipulation of small volumes of fluids typically nanoliters or less within networks of channels that have dimensions of tens to hundreds of micrometers. Li has published 210 papers in leading international journals, 10 book chapters and three books. This work presents a direct currentinsulatorbased dielectrophoretic dcidep approach to simultaneously capture and separate exosomes by size. Potential flow fields are calculated using either an inverse method or a schwarz. Electrokinetically driven microfluidics and nanofluidics rmit. Universityofljubljana facultyofmathematicsandphysics. The talks were centered around three main topics, namely, fundamentals in microfluidics, fundamentals in nanofluidics, and their applications particularly in biological. Extreme microfluidics labelfree of sorting of extremely rare circulating tumor cells. Electrokineticallydriven microfluidics and nanofluidics.
Optoelectrical microfluidics as a promising tool in. He is the editorinchief of an international journal microfluidics and nanofluidics. However, these advantages come with the added complexity of particle manipulation in a microscale environment. Microfluidic system concept concept one system to provide all of the possible required analyses for a given type problem all processing steps are performed on the. He has delivered several named lectures and keynote speeches, including the colburn lecture at the university of delaware, the corrsin lecture at johns hopkins, the pattern lecture at university of colorado and. However, exosome isolation and characterization are the first steps toward designing novel applications. Electrokineticallydriven microfluidics and nanofluidics 1st edition by hsuehchia chang author, leslie y.
1457 1094 477 781 68 1007 32 987 530 970 1445 888 690 45 438 1489 1114 264 635 1437 90 1087 1008 83 342 518 1401 146 576 419 370 74 354 1316 785 726